Table 3.
Applications of some injectable hydrogels for cartilage tissue engineering
| Process | Polymer | Cell types | Model | Study | Year | Reference |
|---|---|---|---|---|---|---|
| Small animal study | HA | MSCs | Minipig | Ha et al. | 2015 | 235 |
| Chitosan | Chondrocytes | Rabbit | Zhao et al. | 2015 | 205 | |
| ACM-BMHP-SAP | MSCs | Rabbit | Lu et al. | 2018 | 236 | |
| Large animal study | Fibrin | ES-like cells | Ovine | Pilichi et al. | 2014 | 204 |
| Fibrin | BMSCs | Equine | Goodrich et al. | 2016 | 201 | |
| Alginate | Chondrocytes or periosteal cells | Sheep | Schagemann et al. | 2009 | 237 | |
| Fibrin | Autologous chondrocytes | Goat | Lind et al. | 2008 | 238 | |
| Aragonite-HA | Not applicable | Goat | Kon et al. | 2015 | 202 | |
| Collagen | MSCs | Monkey | Araki et al. | 2015 | 239 | |
| Clinical study | PEGDA-HA | Not applicable | Human | Flisseeff et al. | 2013 | 206 |
| ChonDux | Not applicable | Human | / | / | 38 | |
| GelRine | Not applicable | Human | / | / | 38 | |
| Commercial | BST-CarGel (Chitosan Scaffold) | Not applicable | Human | Restrepo et al. | 2015 | 207 |
BMSCs, Bone marrow-derived stromal cells; HA, Hyaluronic acid; MSCs, mesenchymal stem cells.