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. 2020 Aug 1;10(21):9767–9778. doi: 10.7150/thno.47882

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Kaplan-Meier curves for distant metastasis-free survival, disease-free survival and overall survival of patients with TFP IC plus CCRT versus patients with CCRT alone stratified according to the PSDM. Plots show (A) distant metastasis-free survival, (B) disease-free survival and (C) overall survival in patients with PSDM low risk scores and (D) distant metastasis-free survival, (E) disease-free survival and (F) overall survival in patients with PSDM high risk scores. Abbreviations: TPF, Taxane-Platinum-5FU regimen; IC, induction chemotherapy; CCRT, concurrent chemoradiotherapy; PSDM, protein-based signature for distant metastasis. HR, hazard ratio; and CI, confidence interval.