Table 1.
Comparison of clinical and angiographic characteristics between patients with BMI < 27 kg/m2 and ≥ 27 kg/m2
| BMI < 27 kg/m2 | BMI ≥ 27 kg/m2 | p value | |
|---|---|---|---|
| N = 6973/15,966 (43.7%) | N = 8993/15,996 (56.3%) | ||
| Age (years) | 65.6 ± 10.5 | 63.7 ± 10.1 | < 0.001 |
| BMI (kg/m2) | 24.3 ± 2.0 | 31.2 ± 3.7 | < 0.001 |
| Female | 23.8 (1663/6973) | 22.8 (2051/8993) | 0.12 |
| Clinical presentation | |||
| Chronic coronary syndromes | 51.6 (3601/6973) | 54.3 (4880/8993) | 0.001 |
| Acute coronary syndromes | |||
| Unstable angina | 12.2 (852/6973) | 13.0 (1169/8993) | |
| NSTEMI | 21.1 (1473/6973) | 21.1 (1900/8993) | |
| STEMI | 15.0 (1047/6973) | 11.6 (1044/8993) | |
| Comorbidities | |||
| Diabetes mellitus | 18.6 (1293/6968) | 30.5 (2745/8987) | < 0.001 |
| Insulin treated | 5.3 (367/6956) | 9.6 (856/8963) | < 0.001 |
| Hypertension | 67.3 (4677/6947) | 78.5 (7038/8965) | < 0.001 |
| Hypercholesterolemia | 65.9 (4446/6751) | 72.6 (6322/8712) | < 0.001 |
| Current smoker | 28.3 (1973/6973) | 24.4 (2195/8993) | < 0.001 |
| PVD | 7.1 (488/6904) | 5.8 (517/8916) | 0.001 |
| COPD | 4.8 (336/6938) | 5.4 (485/8956) | 0.11 |
| Renal impairment* | 12.3 (856/6936) | 14.7 (1315/8945) | < 0.001 |
| Medical history | |||
| Previous bleeding | 0.7 (46/6966) | 0.6 (52/8979) | 0.52 |
| Previous stroke | 2.4 (167/6960) | 2.8 (254/8983) | 0.09 |
| Previous MI | 22.0 (1530/6952) | 24.3 (2180/8968) | 0.001 |
| Previous PCI | 30.9 (2152/6968) | 34.2 (3069/8984) | < 0.001 |
| Previous CABG | 5.8 (406/6967) | 6.0 (537/8986) | 0.69 |
| Procedure | |||
| Radial access | 73.4 (5089/6931) | 74.5 (6670/8950) | 0.12 |
| Number of lesions treated | 0.36 | ||
| One lesion | 68.0 (4698/6913) | 68.2 (6094/8930) | |
| Two lesions | 22.8 (1575/6913) | 23.1 (2066/8930) | |
| Three or more | 9.3 (640/6913) | 8.6 (770/8930) | |
| Average number | 1.4 ± 0.8 | 1.4 ± 0.7 | 0.18 |
| Left main PCI | 2.9 (198/6913) | 2.6 (231/8930) | 0.29 |
| RCA PCI | 37.7 (2607/6913) | 37.5 (3347/8930) | 0.77 |
| LAD PCI | 51.7 (3575/6913) | 50.1 (4476/8930) | 0.047 |
| LCX PCI | 30.7 (2125/6913) | 32.3 (2884/8930) | 0.037 |
| Bypass graft PCI | 1.4 (94/6913) | 1.4 (124/8930) | 0.88 |
| Multivessel PCI | 22.9 (1583/6913) | 22.3 (1991/8930) | 0.37 |
Data are presented as mean ± standard deviation or percentage (number)
*Based on creatinine-estimated GFR (eGFR) clearance of < 60 ml/min/1.73 m2, using the Modification of Diet in Renal Disease (MDRD) formula.
BMI body mass index, PVD peripheral vascular disease, COPD chronic obstructive pulmonary disease, MI myocardial infarction, STEMI ST-elevation myocardial infarction, NSTEMI Non-STEMI, PCI percutaneous coronary intervention, CABG coronary artery bypass graft; RCA: right coronary artery, LAD left anterior descending artery, LCX left circumflex artery