Table 3.

List of the most enriched phenotypes and their corresponding Udu/Gon4l-interacting genes after model organism Phenotype Enrichment Analysis of mouse phenome database.

Phenotype name	BH FDR corrected P-value	Genes with the term
Embryo phenotype	0.023	mcm4, npat, thoc1, bap1, dnmt1, yy1, hdac1
Increased embryonic tissue cell apoptosis	0.028	thoc1, dnmt1
Mortality/aging
Prenatal lethality	0.012	mcm3, mcm4, thoc1, bap1, dnmt1, yy1, sin3a, hdac1
Embryonic lethality, complete penetrance	0.007	mcm4, dnmt1, yy1, hdac1
Embryonic lethality between implantation andsomite formation, complete penetrance	0.036	mcm4, sin3a
Neoplasm
Increased hemolymphoid system tumor incidence	0.007	mcm4, esr2, h2afx
Increased T cell derived lymphoma incidence	0.006	mcm4, h2afx
Cellular phenotype
Abnormal cell proliferation	0.022	mcm3, mcm4, dnmt1, esr2, h2afx, hdac1
Decreased cell proliferation	0.012	mcm3, mcm4, dnmt1, h2afx, hdac1
Chromosomal instability	0.018	mcm4, h2afx
Nervous system phenotype
Abnormal dopamine level	0.014	esr2, pnkd