Skip to main content
. 2020 Aug 26;11:4264. doi: 10.1038/s41467-020-18050-2

Table 1.

Model parameters.

Parameter Units Median 95% CI Information
βP0 (d−1) 1.26 [1.24, 1.28] Estimated
1/δE (d) 4.6 15,26
1/δP (d) 2 15,26
1/η (d) 5 52
1/γI (d) 14 11
1/αI (d) 25 11
βA/βP (1) 0.022 [0.020, 0.030] Estimated
βI/βA (1) 1 11,12
βP1/βP0 (1) 0.89 [0.87, 0.92] Estimated
βP2/βP1 (1) 0.72 [0.70, 0.73] Estimated
MeanβP3/βP2 (1) 0.50 [0.48, 0.51] Estimated
StandarddeviationβP3/βP2 (1) 0.038 [0.025, 0.053] Estimated
Δt0 (d) 35 11
ω 1 2.42 [2.33, 2.52] Estimated

The posterior distribution of the parameters marked as estimated was sampled through the DREAMZS implementation of the Markov chain Monte Carlo algorithm53. For all estimated parameters, we used uninformative priors within biologically meaningful boundaries. Following our previous application11, we assumed σ = 0.25, rS = 0.5, ζ = 0.45, and rE = rP = rA = rR = rS, whereas rI = rQ = rH = 0. Moreover, γQ = γI = γH, γA = 2γI, and αH = αI.