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. 2020 Aug 26;10:14204. doi: 10.1038/s41598-020-70921-2

Figure 13.

Figure 13

(a) Cell viability analysis using Sulforhodamine B (SRB) assay. The results of SRB assay corroborate well with the aforementioned assays. The cellular viability of HCT116 cells remained unperturbed even at highest treated concentration of soluble curcumin whereas MoS2 QDs had shown pronounced killing (< 5%) at 2048 µg/ml concentration. (b) Lactate dehydrogenase assay for cytotoxicity evaluation. The plot shows relative enzyme activity in terms of absorbance. The experiment had three controls parameters, 1. The medium alone; 2. Cells with the medium and 3. The cells treated with 2% Triton X 100. The minimal LDH activity was found in the group treated with soluble curcumin indicating minor cellular lysis while the MoS2 QDs treated group had shown dose dependent cell lysis with maximum LDH activity at the concentration of 2048 µg/ml. [Graphs were generated and analyzed using GraphPad 8.0 (San Diego, CA)].