Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 26;10:14210. doi: 10.1038/s41598-020-71041-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(A) Serpentine channel and lateral filters are modeled as a network of hydrodynamic resistors. The filters ( $R_{f}$ ) in each column are modeled as a group of hydrodynamic resistors in parallel. The serpentine main channel is modeled as a series of hydrodynamic resistors ( $R_{c}$ ), as well as the channel elbows ( $R_{n}$ ). (B) The three basic components (R_f, R_c, and R_n) are interconnected in a hydrodynamic resistor network. Their designations from 1 to 68 in the adjacent column are in a reverse order, just like the flow directions indicated by the red arrows. (C) The mainstream ratio calculated for all filter sizes in the LFAM2 device. (D) The flow pattern observed in the LFAM2 device when a blood sample is pumped through the device. The filter size in the picture is 18 µm and the scale bar is 300 µm. Five representative streaklines are added for easy visualization of the cell trajectory paths.