Figure 3.

Overall stress and strain curves for Control, Fx-Untreated and Fx-BisTreated groups. (a) Normalized stress–strain curves indicating the critical (${\epsilon }_{\mathit{Tissue}}^{\mathit{nUTS}}$) and max tissue strains for each group. Effect sizes (ES) used in the statistical analyses are shown (see Table 2). (b) Fibril-tissue strain curves showing tissue strains to reach peak fibril strain (${\epsilon }_{\mathit{Tissue}}^{maxfibril}$). (c) Mineral-tissue strain curves showing the tissue strains to reach peak mineral strain (${\epsilon }_{\mathit{Tissue}}^{maxmineral}$). Shaded areas represent the 95% confidence intervals for n = 10 donors per group.