Figure 3.

Structure-based sequence alignment. The structures of GePTS1 and PsPTS1, together with earlier structures for DRR206 and AtDIR6, help resolve ambiguities in the alignment, particularly in the last strand (β8). β-Strands in GePTS1 are shown with a dark red arrow, whereas a blue line indicates the loops in between the β-strands. Amino acid numbering (e.g. F48 and D50) is that of GePTS1. GePTS1, G. echinata pterocarpan synthase 1; PsPTS1, P. sativum pterocarpan synthase 1; DRR206, P. sativum (+)-pinoresinol–forming DP; AtDIR6, A. thaliana (–)-pinoresinol–forming DP; GhDIR4, G. hirsutum (+)-gossypol–forming DP.