Table 1.
Ventilator settings and measurements of in vivo individualized shared ventilation
| Individual ventilation | Shared ventilator | |||
|---|---|---|---|---|
| Animal 1 | Animal 2 | Animal 1 | Animal 2 | |
| Ventilator settings | ||||
| Tidal volume (ml) | 600 | 800 | 1400 | |
| PEEP (cmH2O) | 3 | 4 | 3 | 7 |
| FiO2 | 0.3 | 0.3 | 1.0 | |
| I/E ratio | 1:2 | 1:2 | 1:1.5 | |
| Respiratory rate (min−1) | 20 | 20 | 20 | |
| Measured ventilatory values | ||||
| PEEP (cmH2O) | 3 | 5 | 4 | 7 |
| Ppeak vent (cmH2O) | 18 | 32 | 31 | |
| Ppeak circuit (cmH2O) | 19 | 18 | ||
| etCO2 | 31 | 33 | 32 | 29 |
| Blood gas values | ||||
| pH | 7.54 | 7.54 | 7.47 | 7.49 |
| PaO2 (mmHg) | 112 | 230 | 443 | 376 |
| PaCO2 (mmHg) | 31 | 30 | 39 | 36 |
| Hemodynamic values | ||||
| BP (mmHg) | 76/43 | 83/38 | 73/40 | 84/36 |
Table 1 shows the settings of the ventilator per animal and for the shared ventilator in a volume-controlled ventilation. In animal 2, inline PEEP was applied; in animal 1, the flow restriction with our valve was applied to distribute the pressures as desired among the two animals.