Figure 1.

Photographs and radiographs of the feet and hand of the proband´s daughters. (A) Macrodactyly of the great toes of the eldest (upper panels) and youngest daughter (lower panels). The radiograph of the eldest daughter shows iatrogenic bone abnormalities on the distal part of metatarsal 1 after ablation of the pseudo-epiphyses (upper panel; white arrow). The pseudo-epiphyses in the first metatarsophalangeal joint and proximal interphalangeal joint of the youngest daughter are clearly distinguishable (lower panel; white arrows). (B) Left hand of the eldest daughter. The mid- and proximal phalanges of all fingers show pseudo-epiphyses (white square). Carpalia and metacarpals are normal.