REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse monoclonal anti-CCND2 (B-6)	Santa Cruz	Cat#sc376676; RRID:AB_11151389
Rabbit monoclonal anti-EEF1A1	Abcam	Cat#ab157455
Mouse monoclonal anti-Ezrin (3C12)	Abcam	Cat#ab4069; RRID:AB_304261
Rabbit monoclonal anti-FTH1 (D1D4)	Cell Signaling	Cat#4393S; RRID:AB_11217441
Rabbit polyclonal anti-GFAP	Sigma	Cat#G9269; RRID:AB_477035
Chicken polyclonal anti-GFP	Aves	Cat#1020; RRID:AB_10000240
Rabbit polyclonal anti-Homer1	Synaptic Systems	Cat#160003; RRID:AB_887730
Mouse monoclonal anti-MDM2 (2A10)	Abcam	Cat#ab16895; RRID:AB_2143534
Mouse monoclonal anti-PSD95	BD Biosciences	Cat#610495; RRID:AB_397861
Mouse monoclonal anti-RACK1 (B-3)	Clinisciences	Cat#17754; RRID:AB_2247471
Mouse monoclonal anti-VGluT1	Synaptic Systems	Cat#135511; RRID:AB_887879
Mouse monoclonal anti-PMY-647 (12D10)	Sigma	Cat#MABE343-AF647; RRID:AB_2736876
FISH Probes
Ftl1	Bio-Techne	NM_010240.2
Gfap	Bio-Techne	NM_001131020.1
Gjb6	Bio-Techne	NM_001010937.2
Slc1a2	Bio-Techne	NM_001077514.3
Gnb2l1	Bio-Techne	NM_008143.3
Mdm2	Bio-Techne	NM_010786.4
Eef1a1	Bio-Techne	NM_010106.2
Ccnd2	Bio-Techne	NM_009829.3
Fth1	Bio-Techne	NM_010239.2
qPCR probes
Ccnd2	Thermofisher	Mm00438070_m1
Ezr	Thermofisher	Mm00447761_m1
Mdm2	Thermofisher	Mm00487656_m1
Rdx	Thermofisher	Mm00501337_m1
Rps3	Thermofisher	Mm00656272_m1
Rpl8	Thermofisher	Mm00657299_g1
Hsp90ab1	Thermofisher	Mm00833431_g1
Rps14	Thermofisher	Mm00849906_g1
Fth1	Thermofisher	Mm00850707_g1
Slc1a2	Thermofisher	Mm01275814_m1
Gnb2l1	Thermofisher	Mm01291968_g1
Eef1a1	Thermofisher	Mm01973893_g1
Npm1	Thermofisher	Mm02391781_g1
Rplp1	Thermofisher	Mm02601846_g1
Ftl1	Thermofisher	Mm03030144_g1
Eef2	Thermofisher	Mm05700170_g1
Rpl4	Thermofisher	Mm05781370_g1
Cacna1a	Thermofisher	Mm00432190_m1
Slc12a5	Thermofisher	Mm00803929_m1
Grin1 Bsn	Thermofisher Thermofisher	Mm00433790_m1 Mm00464452_m1
RNA45S (18S)	Thermofisher	Mm04277571_s1
Experimental Models: Organisms/Strains
Mouse: C57BL/6J wildtype	Janvier labs	SC-C57J-M
Mouse: Tg(Aldh1l1-eGFP/Rpl10a) JD130Htz	Nathaniel Heintz’s laboratory (Rockefeller University, New York City, NY)	MGI:5496674www.bactrap.org
Mouse: hGfap:eGFP	Max Delbrück Center for Molecular Medicine (Berlin-Buch, Germany)	(Nolte et al., 2001)
Software and Algorithms
ImageJ	https://imagej.nih.gov/ij/	https://imagej.nih.gov/ij/
AstroDot plugin for ImageJ	Our laboratory	Oudart et al., 2020
Virus Strains
Serotype 9 AAV GfaABC1D:eGFP	This paper	N/A
Serotype 9 AAV GfaABC1D:ERGIC-GFP	This paper	N/A
Serotype 9 AAV GfaABC1D:pGolt-mCherry	This paper	N/A
Deposited Data
Raw data and analysis	This paper	GEO: GSE143531
Chemicals, Peptides, and Recombinant Proteins
Puromycin dihydrochloride	Sigma	Cat#P7255