Table 2.
Demographic data, visual acuity, and optical coherence tomography characteristics in four different eGFR groups at baseline.
| A: eGFR >90 (n = 23) | B: eGFR 61-90 (n = 21) | C: eGFR 30-60 (n = 23) | D: eGFR <30(n = 19) | P value | |||
|---|---|---|---|---|---|---|---|
| A vs. B | A vs. C | A vs. D | |||||
| Age (year) | 59.0 ± 10.2 | 61.2 ± 8.0 | 69.2 ± 8.7 | 60.5 ± 10.2 | 0.84 | 0.002 | 0.50 |
| Sex (female) | 61% | 67% | 48% | 42% | 0.33 | 0.37 | 0.20 |
| Hypertension | 65% | 57% | 100% | 74% | 0.76 | 0.004 | 0.74 |
| HbA1c (%) | 7.5 ± 1.2 | 7.2 ± 0.9 | 7.5 ± 1.1 | 6.6 ± 0.8 | 0.57 | 0.77 | 0.030 |
| DR staging | 0.56 | 0.51 | 0.92 | ||||
| Mild NPDR | 0% | 0% | 4% | 5% | |||
| Moderate NPDR | 17% | 10% | 17% | 11% | |||
| Severe NPDR | 26% | 19% | 39% | 26% | |||
| Treatment-naive PDR | 17% | 10% | 22% | 21% | |||
| PDR with PRP | 39% | 62% | 17% | 37% | |||
| LogMAR of BCVA | 0.76 ± 0.35 | 0.68 ± 0.42 | 0.79 ± 0.42 | 0.88 ± 0.37 | 0.17 | 0.97 | 0.35 |
| CFT (μm) | 439 ± 116 | 450 ± 128 | 423 ± 110 | 407 ± 93 | 0.99 | 0.50 | 0.54 |
| Intraretinal cysts | 83% | 95% | 91% | 100% | 0.35 | 0.67 | 0.11 |
| Subretinal fluid | 22% | 24% | 26% | 5% | 1 | 1 | 0.20 |
| Injection number | 5.7 ± 2.2 | 4.0 ± 2.3 | 5.7 ± 2.1 | 4.7 ± 1.8 | 0.018 | 0.95 | 0.18 |
CFT: central foveal thickness; DR: diabetic retinopathy; eGFR: estimated glomerular filtration rate; LogMAR of BCVA: logarithm of the minimum angle of resolution of best-corrected visual acuity; NPDR: nonproliferative diabetic retinopathy; PDR: proliferative diabetic retinopathy; PRP: panretinal photocoagulation.