Table 3.
Univariate and multivariate Cox regression analyses in the training, test, and entire set.
| Variables | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI of HR | p value | HR | 95% CI of HR | p value | |
| Training set (n = 518) | ||||||
| Age | 1.021 | 1.004-1.038 | 0.014 | 1.016 | 0.999-1.034 | 0.055 |
| T stage | 1.574 | 1.183-2.094 | 0.002 | 1.166 | 0.812-1.674 | 0.405 |
| N stage | 1.588 | 1.275-1.979 | <0.001 | 1.269 | 0.893-1.803 | 0.183 |
| M stage | 8.277 | 4.132-16.582 | <0.001 | 3.647 | 1.354-9.825 | 0.011 |
| Stage | 2.202 | 1.616-2.999 | <0.001 | 1.099 | 0.585-2.063 | 0.769 |
| Ten-lncRNA risk score | 4.203 | 2.462-7.176 | <0.001 | 3.775 | 2.202-6.471 | <0.001 |
| Testing set (n = 517) | ||||||
| Age | 1.013 | 0.994-1.032 | 0.170 | |||
| T stage | 1.312 | 0.947-1.819 | 0.103 | |||
| N stage | 1.337 | 1.062-1.682 | 0.013 | 1.113 | 0.758-1.635 | 0.585 |
| M stage | 12.332 | 6.231-24.408 | <0.001 | 11.382 | 3.605-35.933 | <0.001 |
| Stage | 2.068 | 1.452-2.946 | <0.001 | 1.078 | 0.568-2.048 | 0.818 |
| Ten-lncRNA risk score | 2.885 | 1.636-5.088 | <0.001 | 3.196 | 1.803-5.668 | <0.001 |
| Entire set (n = 1035) | ||||||
| Age | 1.018 | 1.005-1.030 | 0.006 | 1.017 | 1.005-1.030 | 0.007 |
| T stage | 1.445 | 1.166-1.791 | <0.001 | 1.068 | 0.823-1.385 | 0.620 |
| N stage | 1.445 | 1.235-1.691 | <0.001 | 1.152 | 0.894-1.483 | 0.274 |
| M stage | 10.125 | 6.233-16.450 | <0.001 | 6.202 | 2.882-13.349 | <0.001 |
| Stage | 2.1347 | 1.691-2.696 | <0.001 | 1.168 | 0.727-1.876 | 0.522 |
| Ten-lncRNA risk score | 3.5227 | 2.388-5.196 | <0.001 | 3.396 | 2.298-5.018 | <0.001 |
HR: hazard ratio. CI: confidence interval.