Figure 9.

Effect of BBR on the PI3K/AKT pathway in HepG2-IR cells. (a) Representative Western blotting results of PI3K p85, pAKT Ser473, AKT, pIRS-1 Ser307, IRS-1, pIRS-2 Ser731, IRS-2, and nucleoprotein NF-κB p65. (b–i) Semiquantitative analysis of PI3K p85, pAKT Ser473, AKT, pIRS-1 Ser307, IRS-1, pIRS-2 Ser731, IRS-2, and nucleoprotein NF-κB p65. The experiments were repeated three times and presented as mean ± SD. ^▲P < 0.05 and ^▲▲P < 0.01, Con vs. model; ^∗P < 0.05 and ^∗∗P < 0.01, model vs. BBR-treated groups.