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. 2020 Aug 12;22(8):e17774. doi: 10.2196/17774

Table 3.

Results of step 2: concept mapping study.

Evaluation approacha

Use of approachb, % “yes” response Familiarity with approachc Proving effectivenessd


Mean % of 3 + 4 (n/N) Mean % of 3 + 4 (n/N)
Pilot/feasibility 58 (SD 32.7) 2.9 (SD 0.5) 2.3 (SD 0.3)

3. Feasibility studye 94 3.6 88 (28/42) 2.6 52 (16/31)

4. Questionnairee 100 3.4 84 (27/63) 2.5 52 (16/31)

8. Single-case experiments or n-of-1 study (N=1) 28 2.5 43 (13/60) 2.0 27 (8/30)

12. Action research study 41 2.6 50 (15/58) 2.3 38 (11/29)

44. A/B testing 25 2.5 45 (13/58) 2.2 36 (10/28)
Development and usability 37 (SD 29.1) 2.5 (SD 0.4) 2.1 (SD 0.3)

5. Focus group (interview) 91 3.2 81 (26/62) 2.3 32 (10/31)

6. Interview 94 3.1 75 (24/62) 2.3 35 (11/31)

23. Think-aloud method 66 2.6 52 (15/59) 1.7 14 (4/29)

25. Cognitive walkthrough 31 2.4 37 (11/59) 1.8 17 (5/30)

27. eHealthf Analysis and Steering Instrument 12 2.4 55 (16/58) 2.4 48 (14/29)

28. Model for Assessment of Telemedicine applications (MAST) 22 2.5 48 (14/59) 2.4 37 (11/30)

29. Rapid review 31 2.0 23 (7/58) 1.8 7 (2/29)

30. eHealth Needs Assessment Questionnaire (ENAQ) 6 2.4 45 (13/58) 2.0 24 (7/29)

31. Evaluative Questionnaire for eHealth Tools (EQET) 3 2.4 52 (15/58) 2.3 41 (12/29)

32. Heuristic evaluation 19 2.2 31 (9/57) 2.1 24 (7/29)

33. Critical incident technique 9 2.0 24 (7/59) 1.8 4 (1/28)

36. Systematic reviewe 94 3.1 67 (20/62) 2.9 69 (20/29)

39. User-centered design methodse 53 3.2 73 (22/62) 2.5 50 (14/28)

43. Vignette study 41 2.2 31 (9/58) 1.6 7 (2/28)

45. Living lab 34 2.5 41 (12/58) 2.3 54 (15/28)

50. Method for technology-delivered health care measures 9 2.3 39 (11/58) 2.1 25 (7/28)

54. Cognitive task analysis (CTA) 16 2.1 23 (7/59) 1.9 18 (5/28)

60. Simulation study 41 2.5 50 (15/60) 2.2 34 (10/29)

62. Sociotechnical evaluation 22 2.3 37 (11/60) 2.1 29 (8/28)
All phases 11 (SD 4) 2.3 (SD 0.2) 2.2 (SD 0.2)

21. Multiphase Optimization Strategy (MOST) 6 2.3 45 (13/58) 2.3 39 (11/28)



26. Continuous evaluation of evolving behavioral intervention technologies (CEEBIT) framework 6 2.4 48 (14/60) 2.3 38 (11/29)

40. RE-AIMg frameworke 19 2.6 61 (17/59) 2.4 52 (14/27)

46. Normalization process model 9 2.0 25 (7/57) 1.9 18 (5/28)

48. CeHResh Roadmap 16 2.4 43 (12/58) 2.3 41 (11/27)

49. Stead et al [82] evaluation framework 12 2.2 38 (11/58) 2.1 22 (6/27)

51. CHEATSi: a generic information communication technology evaluation framework 6 2.3 41 (12/58) 2.1 26 (7/27)

52. Stage Model of Behavioral Therapies Research 9 1.9 21 (6/58) 2.0 22 (6/27)

53. Life cycle–based approach to evaluation 12 2.3 45 (13/58) 2.0 21 (6/28)
Effectiveness testing 45 (SD 23) 2.6 (SD 0.3) 2.6 (0.4)

1. Mixed methodse 87 3.2 81 (26/63) 2.9 65 (20/31)



2. Pragmatic randomized controlled triale 62 3.1 77 (24/63) 3.3 83 (25/30)

7. Cohort studye (retrospective and prospective) 81 2.7 58 (18/61) 2.5 58 (18/31)

9. Randomized controlled triale 91 3.3 71 (22/63) 3.3 74 (23/31)

10. Crossover studye 44 2.7 57 (17/61) 2.7 59 (17/29)
11. Case series 50 2.1 20 (6/60) 1.8 10 (3/29)

13. Pretest-posttest study designe 62 2.6 45 (14/60) 2.5 50 (15/30)

14. Interrupted time-series study 44 2.5 43 (13/59) 2.7 59 (17/29)

15. Nested randomized controlled trial 31 2.3 37 (11/59) 2.8 55 (16/29)

16. Stepped wedge trial designe 56 2.8 70 (21/60) 3.2 90 (26/29)

17. Cluster randomized controlled triale 50 2.8 60 (18/60) 3.1 69 (20/29)

19. Trials of intervention principles (TIPs)e 23 2.5 42 (13/61) 2.5 43 (13/30)
20. Sequential Multiple Assignment Randomized Trial (SMART) 9 2.4 45 (13/58) 2.7 62 (18/29)

35. (Fractional-)factorial design 22 2.3 45 (13/58) 2.2 36 (10/28)

37. Controlled before-after study (CBA)e 37 2.6 50 (15/60) 2.4 52 (15/29)

38. Controlled clinical trial /nonrandomized controlled trial (CCT/NRCT)e 47 2.9 70 (21/60) 2.9 71 (20/28)

41. Preference clinical trial (PCT) 19 2.1 24 (7/58) 2.1 25 (7/28)
42. Microrandomized trial 9 2.2 24 (7/59) 2.4 50 (14/28)
55. Cross-sectional study 72 2.5 40 (12/60) 2.1 29 (8/28)

56. Matched cohort study 37 2.2 30 (9/59) 2.3 46 (13/28)
57. Noninferiority trial designe 53 2.6 47 (14/60) 2.6 48 (14/29)

58. Adaptive designe 19 2.6 52 (15/58) 2.5 50 (14/28)
59. Waitlist control group design 34 2.1 28 (8/59) 2.0 32 (9/28)

61. Propensity score methodology 31 2.1 30 (9/59) 2.0 21 (6/29)
Implementation 54 (SD 28) 2.8 (SD 0.5) 2.6 (SD 0.5)

18. Cost-effectiveness analysis 81 3.4 87 (27/63) 3.2 70 (21/30)



22. Methods comparison study 16 2.0 17 (5/59) 2.0 21 (6/28)

24. Patient reported outcome measures (PROMs)e 84 3.1 80 (24/60) 2.9 73 (22/30)

34. Transaction logfile analysis 25 2.4 45 (13/57) 2.1 21 (6/28)
47. Big data analysise 62 3.0 73 (22/61) 2.8 59 (17/29)

aApproach identification numbers correspond with the numbers used in Figure 3 and Figure 4.

bBased on the rating question: “does your research group use this approach, or did it do so in the past?”; the percentage of “yes” responses is shown.

cBased on the rating question: “according to your opinion, how important is it that researchers with an interest in eHealth will become familiar with this approach?”; average rating scores ranging from unimportant (1) to absolutely essential (4) and percentages of categories 3 plus 4 are represented.

dThe “proving effectiveness” column corresponds with the rating question: “according to your opinion, how important is the approach for proving the effectiveness of eHealth?” Average rating scores ranging from unimportant (1) to absolutely essential (4) and percentages of categories 3 plus 4 are presented.

eThis approach scored above average on the rating questions “familiarity with the approach” and “proving effectiveness, ” which is plotted in the upper right quadrant of the Go-Zone graph (Figure 3).

feHealth: electronic health.

gRE-AIM: Reach, Effectiveness, Adoption, Implementation, and Maintenance.

hCeHRes: Centre for eHealth Research and Disease management.

iCHEATS: Clinical, human and organizational, educational, administrative, ethnical and social explanatory factors in a randomized controlled trial intervention.