Table 3.
Digital data of simplified Rey-Osterrieth Complex Figure Tests.
| Type of digital data analysis | NCa (n=11) | EOADb (n=11) | LOADc (n=16) | Post hoc Dunn-Šidák test (P value) | |||
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NC vs EOAD | NC vs LOAD | LOAD vs EOAD | |
| Pen stroke analysis, mean (SD) |
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Total number of strokes | 24 (7) | 26 (16) | 23 (4) | >.99 | >.99 | >.99 |
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|
Number of long strokes | 14 (4) | 18 (12) | 16 (4) | >.99 | >.99 | >.99 |
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|
Number of short strokes | 8 (1) | 9 (7) | 7 (3) | >.99 | >.99 | >.99 |
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|
Length of strokes (cm) | 4.58 (0.71) | 3.99 (1.48) | 3.50 (0.86) | .34 | .007 d | .90 |
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|
First 5 stroke ratios | 0.91 (0.16) | 0.69 (0.23) | 0.68 (0.28) | .04 | .07 | >.99 |
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|
Speed of the longest stroke (cm/s) | 6.31 (1.86) | 4.41 (2.76) | 4.08 (1.41) | .09 | .01 | >.99 |
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|
Transition time (second) | 1.39 (0.60) | 2.95 (1.83) | 6.23 (7.54) | .045 | .01 | .97 |
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|
Elapsed time of 5 early long strokes (second) | 14.43 (4.62) | 34.86 (19.39) | 23.65 (14.16) | .012 | .04 | .32 |
| Spatial arrangement, mean (SD) |
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||||
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Whole area (cm2) | 84.17 (10.88) | 108.51 (58.81) | 84.01 (33.93) | >.99 | >.99 | >.99 |
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Skeleton area (cm2) | 58.40 (8.79) | 56.34 (20.78) | 55.29 (18.93) | >.99 | >.99 | >.99 |
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|
Horizontal center of the whole area | 0.42 (0.31) | 0.25 (0.67) | –0.23 (0.40) | .60 | <.001 | .11 |
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Vertical center of the whole area | –3.70 (0.69) | –1.22 (1.84) | –1.61 (2.36) | .005 | .01 | .79 |
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Horizontal position of center of mass | 0.28 (0.34) | 0.46 (0.64) | –0.35 (0.59) | .74 | .004 | .01 |
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Vertical position of center of mass | –3.96 (0.83) | –2.05 (1.68) | 1.90 (2.12) | .02 | .007 | .99 |
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Top edge of the whole area | 0.25 (0.62) | –3.98 (3.59) | 2.37 (3.23) | .004 | .19 | .24 |
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Bottom edge of the whole area | –7.64 (1.00) | –6.44 (1.97) | –5.59 (1.85) | .21 | .005 | .80 |
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Top edge of the skeleton area | –1.14 (0.62) | 0.89 (2.45) | 1.10 (3.46) | .03 | .04 | .95 |
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Bottom edge of the skeleton area | –7.64 (1.00) | –6.44 (1.97) | –5.59 (1.85) | .008 | .005 | >.99 |
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Ratio of input | 0.01 (0.02) | 0.25 (0.26) | 0.18 (0.27) | .005 | .12 | .61 |
| Shape similarity, mean (SD) |
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Cross-correlation maximum value | 0.25 (0.02) | 0.19 (0.05) | 0.20 (0.04) | .004 | .002 | .86 |
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Size-rescaled cross-correlation maximum value | 0.14 (0.04) | 0.11 (0.05) | 0.09 (0.05) | .38 | .04 | .67 |
aNC: normal control.
bEOAD: early-onset Alzheimer disease.
cLOAD: late-onset Alzheimer disease.
dItalicization show significant differences at P<.05.