Figure 1.

Flow chart for the treatment of PSC.

The primary treatment of PSC is surgical resection. Patients can be treated preoperatively with radiotherapy or targeted therapy. Adjuvant chemotherapy and/or targeted therapy are recommended after surgery. Patients need to be reviewed every two to four cycles postoperatively. If the disease progresses, it is necessary to change the treatment plan. For patients with poor physical condition, palliative treatment should be provided to prolong the life of the patient as much as possible. Early use of antivascular therapy combined with immunotherapy maximizes patient treatment responses.

PD-1, programmed cell-death protein 1; PD-L1, programmed cell-death ligand 1; PSC, pulmonary sarcomatoid carcinoma; TKI, tyrosine kinase inhibitor.