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(a) Schematic of a Hex–antibody complex in a 1:3 binding ratio. The theoretical molecular weight of this complex is 520 kDa. (b) Schematic of a theoretical Hex–antibody oligomer where some antibodies are bound by multiple carriers, causing formation of a network of proteins. The molecular weight of a large oligomer is much larger than that of the 1:3 Hex–antibody complex. Not drawn to scale.
