Table 1.
Parameter | Normal Diastolic Function | Diastolic Dysfunction | |||||||
---|---|---|---|---|---|---|---|---|---|
20–40 Years | 40–60 Years | ≥60 Years | Impaired Relaxation | Pseudo-Normal Filling | Restrictive Filling | ||||
Male | Female | Male | Female | Male | Female | ||||
MV- Inflow | |||||||||
MV-E (m/s) | 0.79 ± 0.14 | 0.84 ± 0.17 | 0.72 ± 0.16 | 0.77 ± 0.17 | 0.67 ± 0.15 | 0.72 ± 0.17 | |||
MV-A (m/s) | 0.50 ± 0.13 | 0.51 ± 0.12 | 0.61 ± 0.15 | 0.63 ± 0.14 | 0.73 ± 0.16 | 0.76 ± 0.16 | |||
DecT (m/s) | 179.8 ± 46.4 | 176.7 ± 40.1 | 186.6 ± 52.8 | 188.2 ± 39.8 | 217.5 ± 69.7 | 201.5 ± 55.7 | >220 | 140–220 | <140 |
E/A ratio (m/s) | 1.69 ± 0.52 | 1.72 ± 0.52 | 1.22 ± 0.31 | 1.26 ± 0.43 | 0.96 ± 0.27 | 0.99 ± 0.31 | <1.0 | 1.0–2.0 | >2.0 |
Ivrt (m/s) | >110 | 60–100 | <60 | ||||||
Tissue Doppler | |||||||||
e´ septal (cm/s) | 11.9 ± 2.7 | 12.3 ± 2.3 | 9.8 ± 2.6 | 9.7 ± 2.5 | 7.3 ± 2.2 | 7.9 ± 2.3 | <8 | <8 | <8 |
e´ lateral (cm/s) | 16.2 ± 3.6 | 16.6 ± 3.2 | 12.6 ± 3.0 | 12.4 ± 3.0 | 9.5 ± 2.1 | 9.7 ± 3.2 | <10 | <10 | <10 |
e´ mean sept-lat (cm/s) | 14.0 ± 2.9 | 14.5 ± 2.4 | 11.2 ± 2.4 | 11.1 ± 2.5 | 8.5 ± 1.9 | 8.8 ± 2.6 | |||
E/e´ septal | 6.9 ± 1.7 | 6.9 ± 1.6 | 7.8 ± 2.4 | 8.2 ± 2.2 | 9.8 ± 3.0 | 9.7 ± 2.6 | |||
E/e´ lateral | 5.0 ± 1.3 | 5.2 ± 1.3 | 6.1 ± 2.2 | 6.5 ± 2.3 | 7.6 ± 2.1 | 7.9 ± 2.2 | |||
E/e´ mean sep-lat | 5.8 ± 1.4 | 5.9 ± 1.3 | 6.7 ± 2.1 | 7.2 ± 2.0 | 8.4 ± 2.2 | 8.6 ± 2.2 | ≥13 | ≥13 |
Note: Data from Ponikowski et al.6