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. 2020 Aug 21;16:769–785. doi: 10.2147/TCRM.S207117

Table 1.

Normal and Abnormal Values of Echocardiographic Indices of Diastolic Function of Left Ventricle at Rest According to Age Categories, Differentiated for Gender

Parameter Normal Diastolic Function Diastolic Dysfunction
20–40 Years 40–60 Years ≥60 Years Impaired Relaxation Pseudo-Normal Filling Restrictive Filling
Male Female Male Female Male Female
MV- Inflow
MV-E (m/s) 0.79 ± 0.14 0.84 ± 0.17 0.72 ± 0.16 0.77 ± 0.17 0.67 ± 0.15 0.72 ± 0.17
MV-A (m/s) 0.50 ± 0.13 0.51 ± 0.12 0.61 ± 0.15 0.63 ± 0.14 0.73 ± 0.16 0.76 ± 0.16
DecT (m/s) 179.8 ± 46.4 176.7 ± 40.1 186.6 ± 52.8 188.2 ± 39.8 217.5 ± 69.7 201.5 ± 55.7 >220 140–220 <140
E/A ratio (m/s) 1.69 ± 0.52 1.72 ± 0.52 1.22 ± 0.31 1.26 ± 0.43 0.96 ± 0.27 0.99 ± 0.31 <1.0 1.0–2.0 >2.0
Ivrt (m/s) >110 60–100 <60
Tissue Doppler
e´ septal (cm/s) 11.9 ± 2.7 12.3 ± 2.3 9.8 ± 2.6 9.7 ± 2.5 7.3 ± 2.2 7.9 ± 2.3 <8 <8 <8
e´ lateral (cm/s) 16.2 ± 3.6 16.6 ± 3.2 12.6 ± 3.0 12.4 ± 3.0 9.5 ± 2.1 9.7 ± 3.2 <10 <10 <10
e´ mean sept-lat (cm/s) 14.0 ± 2.9 14.5 ± 2.4 11.2 ± 2.4 11.1 ± 2.5 8.5 ± 1.9 8.8 ± 2.6
E/e´ septal 6.9 ± 1.7 6.9 ± 1.6 7.8 ± 2.4 8.2 ± 2.2 9.8 ± 3.0 9.7 ± 2.6
E/e´ lateral 5.0 ± 1.3 5.2 ± 1.3 6.1 ± 2.2 6.5 ± 2.3 7.6 ± 2.1 7.9 ± 2.2
E/e´ mean sep-lat 5.8 ± 1.4 5.9 ± 1.3 6.7 ± 2.1 7.2 ± 2.0 8.4 ± 2.2 8.6 ± 2.2 ≥13 ≥13

Note: Data from Ponikowski et al.6