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. Author manuscript; available in PMC: 2020 Aug 27.
Published in final edited form as: J Am Chem Soc. 2015 Apr 16;137(16):5363–5371. doi: 10.1021/ja5117809

Table 2. Peptides with identical strands (KWRWRTR and RKIKRWY) but different connecting units.

(All peptides containing Cys are oxidized, with disulfide bonds between strands.)

Name Sequence description TM (°C, CD) 300 K χF (NMR)
C KWRWRTR--C--RKIKRWY (homodimer) 44 0.95
YWRKIKR--C--RTRWRWK
CIC KWRWRTR-CIC-RKIKRWY (homodimer) 58 0.96
YWRKIKR-CIC-RTRWRWK
pP KWRWRTR-p (hairpin monomer) 36 0.88
YWRKIKR-P
Half KWRWRTR--CR (hairpin-like heterodimer) 24 0.66
YWRKIKR--CR