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Uptake of NPs by spheroid surface cells. Representative optical sections of cells on the surface. Overlay of pseudocolored images of nuclear-stained cells (green) on the spheroids’ surface, treated with the various lipid-based NPs (red): PEG-Lip (A), Lip (B), rHDL (C), and LPX (D). Intensity and contrast levels were kept constant, and scale bars correspond to 10 μm.
