Figure 2.

Summary of hormone levels across different reproductive states in women, and known effects on memory and sleep. Left panel summarizes findings in women of reproductive age (with normal ~28-day cycles), the middle panel for women in perimenopause, and the right panel for women in postmenopause. The top bar summarizes hormone levels during the 3 reproductive states, with menopausal symptoms, memory findings and sleep disorder prevalence underneath. Specific findings with respect to how sleep is measured are presented in the middle and lower bars. Thick colored bars within each cell indicate higher levels of symptoms/memory/sleep parameters, and colored dots indicate incomplete/unknown information. E2 = 17β-estradiol; EEG = electroencephalography; EMG = electromyography; EOG = electrooculography; FSH = follicle stimulating hormone; N3 = nonrapid eye movement stages 1-3; OVX = ovariectomized; P = Progesterone; SWA = slow-wave activity; SWS = slow-wave sleep; REM= rapid eye movement; RLS = restless legs syndrome; WASO = waking after sleep onset.