Figure 8.

Omipalisib inhibited the growth of Esophageal squamous cell carcinoma (ESCC) in vivo. (A) Representative image of mice administered different doses of omipalisib at the end of the experiment. (B) Tumor volume was calculated by the following equation: volume=long diameter×(short diameter)²/2. (C) Body weight was recorded every 2 days during the course of omipalisib administration. (D) Protein expression in tumor tissue from KYSE150-bearing mice by Western blot. (E) Density analysis of protein bands were performed with ImageJ software. (* P<0.05, ** P<0.01, *** P<0.001).