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. 2020 Aug 27;20:814. doi: 10.1186/s12885-020-07216-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Establishment and validation of the prognostic model for overall survival based on significant DEGs; a Receiver operating characteristic curves of prognostic signature in the training cohort; b The survival curve showed the different overall survival status between high- and low-risk patients. c The heat map showed the expression of prognostic genes in the training cohort. d The risk curve of each sample reordered by risk score; e The scatter plot showed the overall survival status of osteosarcoma patients in the training cohort; f Receiver operating characteristic curves of prognostic signature in validation cohort; g The survival curve showed the different overall survival status between high- and low-risk patients. h The heat map showed the expression of prognostic genes in the validation cohort. i The risk curve of each sample reordered by risk score; j The scatter plot showed the overall survival status of osteosarcoma patients in the validation cohort