Table 2.
Comparison of clinical characteristics between endometrial cancer patients with and without high-risk features1, n (%)
| Characteristics | Patients with high-risk features (n = 74) | Patients without high-risk features (n = 54) | P value |
| Age (yr), mean ± SD | 60.1 ± 10.7 | 53.7 ± 10.2 | 0.001 |
| BMI (kg/m2), mean ± SD | 27.1 ± 7.8 | 28.5 ± 7.1 | 0.32 |
| Obese (BMI > 30 kg/m2) | 16 (21.6) | 21 (38.9) | 0.05 |
| Nulliparous | 41 (47.7) | 26 (48.1) | 0.48 |
| Postmenopause | 59 (79.7) | 30 (55.6) | 0.006 |
| Coexisting medical diseases | 46 (62.2) | 34 (63.0) | 1.00 |
| Coexisting benign gynecologic diseases | 42 (56.8) | 30 (55.56) | 1.00 |
| CA125 level, median (min-max) | 27.0 (7.1-786.8) | 16.3 (5.3-432.1) | 0.002 |
| HE4 level, median (min-max) | 130.6 (39.4-1719.0) | 81.7 (30.5-293.9) | 0.005 |
1High risk features included grade 3 tumors, large tumor sizes, deep myometrial invasion, lymphovascular space invasion, cervical metastasis, extrauterine metastasis and nodal metastasis. BMI: Body mass index; CA125: Cancer antigen 125; HE4: Human epididymis protein 4.