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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Lancet Digit Health. 2019 Oct 17;1(7):e353–e362. doi: 10.1016/S2589-7500(19)30159-1

Figure 1.

Figure 1.

Comparison of the area under the time dependent receiver operating characteristic curve (AUC) at cut-off time year = 1, 2, and 3 among two risk predictors: ML and Lung-RADS in the NLST training (N=25,097) samples, and three risk predictors, including volume doubling time (VDT), in the PanCan validation (N=2,294) samples. The VDT cannot be reliably estimated in the NLST sample. In the NLST, the p-values of AUC difference between ML and Lung-RADS were <0.001 in all three years. In PanCan, the p-values of AUC difference between ML and Lung-RADS were 0·202, 0·048, and 0·028 for years 1, 2, and 3 respectively; the p-values of AUC difference between ML and VDT were <0.001 for all three years.