Fig. 4.

Immediate post-operative graft function and systemic fibrinolytic status are predictive of longer term graft function. Kidney recipients were divided into 4 cohorts based post-operative day 1 (POD1) creatine levels and lytic response on a high dose tPA (150 ng/ml) TEG. Patients with a >50% reduction in creatinine from pre-op to POD1 were considered to have a good graft function (+Good Graft). Recipients with > or = 23% lysis 30 min after reaching maximum clot amplitude (LY30) on a POD1 high dose tPA TEG were considered to have an elevated LY30 (+High LY30). Group 1 had significantly lower creatinine levels at 6, 12, and 24 months compared to Group 4. ∗, ∗∗, and ∗∗∗ denote statistical significance (p < 0.05).