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Molecular mechanism of MRC-PPL@PSO. The expression of PI3K/AKT, MAPK and NF-κB signaling pathway proteins p-P38, P38, p-Akt, Akt and NF-κB was determined by (a) western blot and (c–d) quantification analysis. Each data point represents mean ± s.d (n = 3). *, # indicate p < 0.05; **, ## indicate p < 0.01; ***, ### indicate p < 0.001
