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. 2020 Aug 25;6(3):e20872. doi: 10.2196/20872

Table 3.

Most statistically significant conditions associated with increased risk of coronavirus disease (COVID-19) complications in age-stratified patient groups.

Condition Age group Patient counts, n ORa (95% CI) P valueb


With condition Without condition



Complicated Noncomplicated Complicated Noncomplicated

Obesity 18-50 years 14 356 7 1977 11.09 (4.15-32.67) <.001
Depression 18-50 years 7 229 14 2104 4.59 (1.55-12.3) .03
Hypertension 18-50 years 4 72 17 2261 7.37 (1.76-23.41) .04
Liver disease 18-50 years 5 125 16 2208 5.51 (1.55-16.07) .04
Chronic kidney disease 50-65 years 14 87 27 683 4.06 (1.89-8.38) .005
End stage renal disease 50-65 years 5 8 36 762 13.11 (3.21-48.19) .006
Neurological disorders ≥65 years 54 113 57 317 2.65 (1.69-4.17) <.001
Chronic kidney disease ≥65 years 70 174 41 256 2.51 (1.6-3.97) .001
Other cardiovascular diseases ≥65 years 36 70 75 360 2.46 (1.49-4.05) .006
Cognitive impairment ≥65 years 28 52 83 378 2.45 (1.4-4.22) .02
Home care ≥65 years 16 22 95 408 3.12 (1.47-6.48) .02
Hypertension ≥65 years 82 249 29 181 2.05 (1.27-3.4) .03
Cardiovascular diseases ≥65 years 50 129 61 301 1.91 (1.22-2.99) .03
Nursing home ≥65 years 20 35 91 395 2.48 (1.29-4.65) .04

aOR: odds ratio. ORs greater than 1 suggest an increased risk for COVID-19 complications in patients with the noted condition.

bIn each stratum, rows are sorted ascendingly by P value.