Table 3:
Adjusted association between baseline opioid use and the odds of successful stabilization on buprenorphine and a post-hoc model contrasting subjects with acute prescription opioid use and persistent prescription opioid use at baseline.
| Odds of successful stabilization in full cohort N=6,756 | Odds of successful stabilization in prescription opioid misusers N=2,978 | |||
|---|---|---|---|---|
| aOR | 95% CI | aOR | 95% CI | |
| Baseline Opioid Use | ||||
| No Prescription Opioid Use | 1 | - | N/A | N/A |
| Acute Prescription Opioid Use | 1.53 | (1.37–1.72) | 1 | - |
| Persistent Prescription Opioid | ||||
| Use | 2.43 | (2.08–2.85) | 1.60 | (1.35–1.90) |
| Baseline Controlled Substance Use | ||||
| Benzodiazepines | 0.9 | (0.78–1.04) | 1.13 | (0.94–1.36) |
| Amphetamines | 1.29 | (1.06–1.58) | 1.01 | (0.79–1.30) |
| Patient Age | ||||
| 15–34 | 1 | - | 1 | - |
| 35–44 | 1.33 | (1.18–1.50) | 1.13 | (0.92–1.39) |
| 45–54 | 1.35 | (1.16–1.58) | 1.34 | (1.06–1.70) |
| 55–64 | 1.22 | (1.03–1.44) | 1.06 | (0.84–1.35) |
| 65 and older | 0.95 | (0.76–1.19) | 0.87 | (0.65–1.16) |
| Payment Type | ||||
| Cash | 1 | - | 1 | - |
| Insured | 1.51 | (1.35–1.69) | 1.18 | (0.98–1.43) |
| Initial Buprenorphine Dose | ||||
| < 12 mg/day | 1 | - | 1 | - |
| ≥12 mg/day | 1.31 | (1.19–1.45) | 1.15 | (0.99–1.33) |
| Rurality | ||||
| Rural | 1 | - | 1 | - |
| Urban | 1.22 | (1.04–1.43) | 0.87 | (0.67–1.13) |