. Author manuscript; available in PMC: 2020 Aug 27.

Published in final edited form as: J Am Stat Assoc. 2017 Jul 13;112(518):508–520. doi: 10.1080/01621459.2016.1228534

Table 1:

The average and standard deviation (SD) of the percentage of correct selection (PCS) of target doses across 32 possible biomarker patterns under the proposed design, the direct approach, and the dose-only design.

Method	PCS	1	2	3	4	5	6	7	8
Method	PCS	Scenario
Proposed	Mean	0.697	0.710	0.708	0.775	0.729	0.697	0.683	0.820
Proposed	SD	0.18	0.21	0.14	0.30	0.24	0.11	0.27	0.17
Direct approach	Mean	0.589	0.829	0.815	0.637	0.601	0.489	0.650	0.480
Direct approach	SD	0.16	0.14	0.06	0.42	0.23	0.32	0.30	0.27
Dose-only	Mean	0.461	0.510	0.501	0.500	0.455	0.195	0.285	0.257
Dose-only	SD	0.26	0.23	0.16	0.22	0.30	0.02	0.0003	0.08