Skip to main content
. Author manuscript; available in PMC: 2020 Aug 27.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2019 Jan 28;28(2):293–302. doi: 10.1158/1055-9965.EPI-18-0584

Figure 1.

Figure 1

A) Fraction of BRCA1/2 founder mutations identified by percent of Ashkenazi-Jewish women tested.
  • Carrier-probability thresholds of 0.56%, 0.78%, 5%, and 10% are indicated vertically.
  • Table gives values of positive predictive value (PPV) and the complement of the negative predictive value (cNPV) for each threshold.
B) Fraction of BRCA1/2 founder mutations identified by percent of subgroup tested, for women under 40 (solid line) and women 40 and older (dashed line).
  • Carrier-probability thresholds of 0.84%, 1%, 5%, and 10% are indicated vertically for women under 40.
  • Thresholds of 0.48%, 0.76%, 5%, and 10% are indicated horizontally for women over 40.
  • Table gives values of positive predictive value (PPV) and the complement of the negative predictive value (cNPV) for each threshold.