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Correlation analysis between standardized mean difference (SMD) of the MRI outcomes and histological markers of (re-)myelination (A) or neuroinflammation (B). The analysis indicates a statistically significant correlation between SMDs of non-contrast-enhanced MRI outcomes and SMDs of (re-)myelination (r = 0.63, p < 0.001). No statistically significant correlation was found between SMDs of MRI outcomes and neuroinflammation.
