Table 1.

Pros and cons of cancer drug screening models.

Model	Cost	Time	Manipulate	Stability	Condition	Source
Commercial 2D cell lines	+	+	+	+	+	+
PDX	+++	+++	+++	++	++	+++
Organoid	+++	++	++	+++	+++	+++

+: Cost low; timesaving; easy to manipulate; poor stability; easy to culture; easy to get.

++: Degree between + and +++.

+++: Cost high; time-consuming; hard to manipulate; good stability; hard to culture; hard to get.

PDX (patient-derived xenograft).