Table 5.
Outcome | Relative risk [95% CI] | P value | NNT [95% CI] |
---|---|---|---|
Composite morbidity scorea ≥2 | 0.451 [0.213–0.952] | 0.037 | 3.869 [2.095–25.227] |
IVH | 0.396 [0.159–0.978] | 0.047 | 4.332 [2.295–38.675] |
IVH and/or death | 0.364 [0.164–0.808] | 0.013 | 3.143 [1.878–9.623] |
BPD | 0.100 [0.014–0.735] | 0.024 | 3.444 [2.145–8.741] |
BPD and/or death | 0.238 [0.075–0.759] | 0.015 | 3.431 [2.069–10.047] |
NAC N-acetylcysteine, IVH intraventricular hemorrhage, BPD bronchopulmonary dysplasia, CI confidence interval, NNT number needed to treat.
aComposite of culture-proven sepsis (any type), IVH grades 3 and 4, ROP grades 2–4, NEC grades 2–4, PVL, BPD, and/or death.