Table 1. The change of body weight, food intake and blood variables.

	Chow	HFD	HYP
Initial body weight(g)	39.7 ± 2.9	50.1 ± 5.2	51.2 ± 3.8
Final body weight(g)	38.1 ±1.6	48.2 ± 3.6	48.3 ± 2.3†
Body weight gain(g)	-1.6 ± 1.6	-1.9 ± 3.6	-3.1 ± 2.3
Food intake(g/day)	4.4 ± 0.4	3.2 ± 0.4	3.3 ± 0.6
Serum glucose(mmol/L)	10.7 ± 2.1	12.7 ± 1.4	13.0 ± 1.3
Serum Insulin(μU/mL)	1.9 ± 0.0	2.0 ± 0.1	1.9 ± 0.0
HOMA-IR	0.9 ± 0.2	1.1 ± 0.1	1.1 ± 0.1

Values represent the mean ± S.D. (n = 10). Homeostasis Model Assessment was used to calculate an index of insulin resistance as insulin (μU/mL) × glucose (mmol/L)/22.5. † p < 0.05 vs. initial.