Impact of a perturbation in M on fibrillization. During the perturbation time, tpert, the number of microglia M is reduced 10-fold. F is depleted relative to its steady-state value before perturbation. The inset diagram on the left side shows the concentration of fAβ at the end of the perturbation period, Fpert. The inset diagram on the right side shows the recovery time, trecov, as a function of the perturbation period. The perturbation time in the inset diagrams is plotted in the units of days. R = 1.2 × 10−3 = 0.92 Rc. To see this figure in color, go online.