Figure 6.
Intervention strategies. The critical production rate Rc, normalized to its nominal value Rcn, as a function of drug efficacies. The treatment strategy is increasing the value of Rc as much as it exceeds the actual production rate R. This happens when a drug decreases the parameters R or kp or increases any other parameter. εx is the efficacy of a drug applying to parameter x. (A) Rc/Rcn for single therapies. (B) and (C) Rc/Rcn for two different combination therapies. To see this figure in color, go online.