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. 2020 Aug 17;16(8):e1008074. doi: 10.1371/journal.pcbi.1008074

Fig 1. Observed (left) and simulated (right) pressure-volume loops in HF-rEF patients in the SOLVD study at baseline and after 1 year of treatment with placebo or enalapril [42].

Fig 1

The model reproduces the baseline P-V loop, rightward shift over time in the placebo group, and the leftward shift in the enalapril group.