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. 2019 Oct 8;32(6):283–292. doi: 10.1016/j.sdentj.2019.09.008

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — A: IHC with anti-CD68 antibody in tissues containing titanium particles (highlighted), only inflammatory cells around the particles are positive. B: IHC with anti-CD68 antibody in tissues without titanium particles. Arrow shows inflammatory cells with intense CD68 positivity. C: IHC with anti-TGF-β antibody in tissues containing titanium particles (highlighted), only inflammatory cells around the particles are positive. D: IHC with anti-CD68 antibody in tissues without titanium particles and minimal inflammatory cells positivity. E: IHC with anti-RANKL antibody in tissues containing titanium particles (highlighted), only inflammatory cells around the particles are positive. F: IHC with anti-RANKL antibody in tissues without titanium particles, certain inflammatory cells, morphologically identified as macrophages show intense positivity (arrow). G: IHC with anti-IL33 antibody in tissues containing titanium particles (highlighted), most inflammatory cells around the particles are positive. H: IHC with anti-IL33 antibody in tissues without Ti particles, some inflammatory cells, show intense positivity (arrow). Images are at 200× magnification.