Table 2.
The results of a univariate regression analysis for predicting the survival of 47 patients with OSCC.
| Variables | OS |
CSS |
PFS |
|||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | p-Value | Hazard ratio (95% CI) | p-Value | Hazard ratio (95% CI) | p-Value | |
| Age, years | ||||||
| ≤65 | 1.534 (0.605–3.429) | 0.344 | 2.086 (0.800–4.903) | 0.982 | 1.014 (0.32–3.69) | 0.982 |
| >65 | ||||||
| Gender | ||||||
| Male | 1.113 (0.539–2.301) | 0.770 | 0.592 (0.17–1.82) | 0.364 | 0.592 (0.17–1.82) | 0.364 |
| Female | ||||||
| T stage | ||||||
| T1 | 0.777 (0.220–3.308) | 0.715 | 7.003 (1.84–32.5) | 0.004⁎⁎ | 7.003 (1.84–32.5) | 0.004⁎⁎ |
| T2 | ||||||
| T3 | ||||||
| T4 | ||||||
| N stage | ||||||
| N0 | 1.350 (0.533–3.621) | 0.532 | 5.844 (1.24–36.1) | 0.024⁎ | 5.844 (1.24–36.1) | 0.024⁎ |
| N1 | ||||||
| N2b | ||||||
| N2c | ||||||
| Primary site | ||||||
| Tongue | 0.108 (0.020–0.444) | 0.001⁎⁎ | 3.135 (0.61–17.4) | 0.169 | 3.135 (0.61–17.4) | 0.169 |
| Mandible | ||||||
| Maxilla | ||||||
| Oral floor | ||||||
| Buccal mucosa | ||||||
| Patate | ||||||
| WPOI | ||||||
| 1 | 0.608 (0.128–3.469) | 0.561 | 1.262 (0.36–4.08) | 0.707 | 1.262 (0.36–4.08) | 0.707 |
| 2 | ||||||
| 3 | ||||||
| 4 | ||||||
| RECIST | ||||||
| CR | 5.702 (1.329–27.079) | 0.019⁎ | 0.101 (0.02–0.38) | <0.001⁎⁎ | 0.101 (0.02–0.38) | <0.001⁎⁎ |
| PR | ||||||
| NC | ||||||
| OPNI status | ||||||
| High | 2.825 (1.327–6.060) | 0.007⁎⁎ | 3.308 (1.08–11.6) | 0.035⁎ | 3.308 (1.08–11.6) | 0.035⁎ |
| Low | ||||||
Abbreviation: OSCC: Oral squamous cell carcinoma. WPOI: Worst pattern of invasion. RECIST: Response Evaluation Criteria in Solid Tumors. CR: Complete response. PR: Partial response. NC: No change. OPNI: Onodera's prognostic nutritional index. CI: confidence interval. OS: overall survival. CSS: cause-specific survival. PFS: progression-free survival.
⁎
p < .05.
⁎⁎
p < .01.