Figure 1.

Characterization and Comparison of MyC-CaP:hPSMA⁺ LDH-A KD and NC Cells In Vitro

(A) ddPCR of LDH-A mRNA expression (p = 0.0004). (B) Western blotting (LDH-A/β-actin density ratio not shown in figure) (p < 0.045). (C) LDH enzyme activity (p < 0.0001). (D) VEGF-A secretion over 24 h (p = 0.0006). (E) ¹⁸F-FDG uptake (p = 0.037). Values are from at least three independent experiments. Mean ± SEM; two-tailed p test. (F) In vitro growth profiles: doubling times were 17.2 ± 0.6 h (KD) and 14.7 ± 0.5 h (NC) (p = 0.009).