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. 2020 Jul 25;18:372–381. doi: 10.1016/j.omto.2020.07.007

Figure 2.

Figure 2

DY-635 Uptake Depends on the Presence of OATP1B3

(A) Quantitative real-time PCR of mRNA expression of OCT1 and OATP1B3 genes after siRNA knockdown in K562 cells. (B and C) Uptake of 100 nM DY-630 (B) and DY-635 (C) from both non-transfected K562 cells (NTCs) and K562 cells immediately before and 24, 48, and 72 h after transfection with OCT1, OATP1B3, or scrambled siRNA. KD, knockdown. RFU, relative fluorescence units. ∗p < 0.05.