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. 2020 Aug 12;23(9):101457. doi: 10.1016/j.isci.2020.101457

Figure 6.

Figure 6

Overexpression of STRAP or NME1 Is Sufficient to Promote Neurite Growth in SH-SY5Y Cells

(A) Graph and representative photomicrographs showing NME1 expression in SH-SY5Y cells transfected with control or NME1 expression plasmid.

(B–D) (B and C) Graphs of neurite length as percentages of control and (D) representative photomicrographs of SH-SY5Y cells transfected with plasmids overexpressing NME1 or STRAP and cultured with or without 100 ng/mL GDF5 for (B) 36 h or (C) 72 h, as indicated. Data are mean ± SEM from three independent experiments (n = 3) (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 versus siSCR control or as indicated. n.s. = not significant; two-way ANOVA with post-hoc Fisher's LSD test or Student's t test where appropriate).