Fig. 3.

Variants detected in HBV surface (S) genes, their positions, and prevalence.

As shown, 96/302 S gene sequences had mutations localised for the vast majority (82/96) in the preS2 domain at positions 38–55 (EcoRI nomenclature). Of these, 53% lost 12, 15, or 18 bp (shades of orange, green, and blue, respectively). Corresponding amino acid changes are shown using a sequence logo. The thickness of the bar reflects the frequency of the deletion. The other mutations (14/96) were localised elsewhere in the S genes. n.a., not applicable; WT, wild type.