Table 3.
Characteristics of HBsAg-positive controls by the presence of preS2Δ38–55 deletions and different HBV genotypes (n = 211).
| Variables | PreS2Δ38–55 |
HBV genotypes |
||||
|---|---|---|---|---|---|---|
| Absent (n = 170) | Present (n = 41) | p value | E (n = 188) | A (n = 23) | p value | |
| Demographic factors | ||||||
| Gender | ||||||
| Women | 47 (85) | 8 (15) | 0.3 | 49 (89) | 6 (11) | 0.9 |
| Men | 123 (79) | 33 (21) | 139 (89) | 17 (11) | ||
| Age (years) | ||||||
| <40 | 134 (82) | 30 (18) | 0.4 | 145 (88) | 19 (12) | 0.6 |
| ≥40 | 36 (77) | 11 (23) | 43 (91) | 4 (9) | ||
| Birth place | ||||||
| Rural | 114 (78) | 32 (22) | 0.2 | 131 (90) | 15 (10) | 0.7 |
| Urban | 56 (86) | 9 (14) | 57 (88) | 8 (12) | ||
| Family history of liver cancer | ||||||
| No | 161 (81) | 39 (19) | 0.9 | 181 (90) | 19 (10) | 0.005 |
| Yes | 9 (82) | 2 (18) | 7 (64) | 4 (36) | ||
| Lifestyle factors | ||||||
| Alcohol intake | ||||||
| Never | 162 (81) | 38 (19) | 0.5 | 180 (90) | 20 (10) | 0.07 |
| Ever | 8 (73) | 3 (27) | 8 (73) | 3 (27) | ||
| AFB1 exposure | ||||||
| No | 44 (73) | 16 (27) | 0.7 | 54 (90) | 6 (10) | 0.2 |
| Yes | 11 (79) | 3 (21) | 14 (100) | 0 | ||
| Virological factors | ||||||
| HBeAg seropositivity | ||||||
| Negative | 155 (80) | 38 (20) | 0.8 | 171 (89) | 22 (11) | 0.4 |
| Positive | 15 (83) | 3 (17) | 17 (94) | 1 (6) | ||
| HBV DNA (IU/ml) | ||||||
| <2,000 | 125 (81) | 30 (19) | 0.9 | 137 (88) | 18 (12) | 0.8 |
| 2,000–106 | 32 (80) | 8 (20) | 36 (90) | 4 (10) | ||
| ≥106 | 13 (81) | 3 (19) | 15 (94) | 1 (6) | ||
| HBsAg levels (IU/ml) | ||||||
| <10,000 | 46 (74) | 16 (26) | 0.3 | 48 (77) | 14 (23) | <0.001 |
| ≥10,000 | 87 (81) | 21 (19) | 103 (95) | 5 (5) | ||
| Genotype | ||||||
| E | 154 (82) | 34 (18) | 0.2 | n.a. | n.a. | |
| A | 16 (70) | 7 (30) | n.a. | n.a. | ||
| Anti-HCV | ||||||
| Negative | 170 (81) | 41 (19) | n.a. | 188 (89) | 23 (11) | n.a. |
| Positive | 0 | 0 | 0 | 0 | ||
| Anti-HDV | ||||||
| Negative | 168 (80) | 41 (20) | 0.6 | 187 (89) | 22 (11) | 0.7 |
| Positive | 1 (100) | 0 | 1 (100) | 0 | ||
| Anti-HIV | ||||||
| Negative | 165 (80) | 41 (20) | 0.3 | 184 (89) | 22 (11) | 0.4 |
| Positive | 4 (100) | 0 | 3 (75) | 1 (25) | ||
Data are presented as n (%).
AFB1, aflatoxin B1; n.a., not applicable.