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. 2020 Feb 29;7(3):359–369. doi: 10.1016/j.gendis.2020.02.002

Figure 1.

Fig. 1

Two putative types of tumor recurrence after curative therapy for hepatocellular carcinoma. After surgical removal or ablation of primary tumors, there are two putative types of tumor recurrence. The first one was the growth from the disseminated tumor cells that have been spread from the primary tumor before curative therapy (type 1 recurrence). The other one was from de novo carcinogenesis in the residual liver because of hepatitis or liver cirrhosis (type 2 recurrence).