. 2020 Aug 19;6(8):e04602. doi: 10.1016/j.heliyon.2020.e04602

Table 3.

Effect of EaF10 on the levels of serum markers related to hepatic dysfunction.

Name of serum markers	Level of serum markers
Name of serum markers	Control	CCl₄	CCl₄ + Sil (100mg/Kg)	CCl₄ + EaF10 (25mg/Kg)	CCl₄ + EaF10 (100mg/Kg)
ALT (IU/L)	34.48 ± 5.26	87.68 ± 7.56^a	40.77 ± 8.42^b	61.36 ± 4.73^b	45.24 ± 8.07^b
AST (IU/L)	19.23 ± 6.07	69.25 ± 7.56^a	28.61 ± 7.33^b	42.07 ± 5.89^b	27.51 ± 4.73^b

Mice in different groups were treated as indicated in the material and methods section. Hepatic dysfunction related to CCl4-hepatotoxicity was determined by quantifying the serum activities (ALT) and (AST). Values are expressed as means ± SD, n = 6; ^a values significantly different compared to normal control group (P˂0.05); ^b values significantly different compared to CCl₄-intoxicated group (P˂0.05) using Bonferroni's test. Control: normal control group; CCl₄: CCl₄-intoxicated group alone; CCl₄+Sil (100mg/Kg): CCl₄-intoxicated + silymarin (100mg/Kg)-treated group; CCl₄ + EaF10 (25mg/Kg): CCl₄-intoxicated + EaF10 (25mg/Kg)-treated group; CCl₄ + EaF10 (100mg/Kg): CCl₄-intoxicated + EaF10 (100mg/Kg)-treated group. ALT: alanine aminotransferase; AST: aspartate aminotransferase.