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. 2020 Jul 29;14:8–16. doi: 10.1016/j.ijpddr.2020.07.001

Table 1.

List of drug classes and anthelmintics available for treating nematodes, trematodes and cestodes discovered pre- and post-2000.

Drug Class Nematode (roundworm) Trematode (fluke) Cestode (tapeworm)
Classes discovered pre-2000
Benzimidazoles Albendazole Albendazole Albendazole Fenbendazole
Febantel Triclabendazole Oxfendazole
Fenbendazole
Flubendazole
Mebendazole
Oxfendazole
Oxibendazole
Thiabendazole
Salicylanilides Closantel Closantel Closantel
Rafoxanide Rafoxanide Rafoxanide
Disophenol Oxyclozanide Niclosamide
Nitroscanate Resorantel
Nitroscanate
Pyrazinoisoquinolones Oxamniquine Epsiprantel
Praziquantel Praziquantel
Sulphonamide Clorsulon
Imidazothiazole/Tetrahydropyrimidines Levamisole
Morantel
Pyrantel
Oxantel
Organophosphates Dichlorvos
Haloxon
Napthalofos
Macrocylic lactones Abamectin
Doramectin
Eprinomectin
Ivermectin
Moxidectin
Milbemycin oxime
Selamectin
Other Piperazine
Diethylcarbamazine
Doxycycline (anti-Wolbachia)
Melarsomine
Nitroxynil


Post-2000 Cyclic octadepsipeptide
Aminoacetonitrile derivatives Nitroxynil
Spiroindole Derquantel